I don't have any personal experience with the tool but I have heard of it and I am pretty sure it integrates with 100. Cypress is the document management solution of choice for BCS Prosoft in San Antonio and they are primarily a 100 shop.
We at CS3 move Altec's docLink instead. While it has a higher price point, it uses MS SQL as a backend database rather than a proprietary database engine and we prefer that. Additionally, docLink is now a Sage OEM product.
Hope that helps.